Pro-atherogenic lipid profile in pulmonary tuberculosis patients with concurrent insulin resistance

Background. The problem of studying lipid metabolism in patients with tuberculosis is interest to scientists around the world. purpose study - investigate profile pulmonary concurrent insulin resistance. Materials and methods. Forty-one were examined. Insulin resistance index (HOMA-IR), total cholesterol level (TC), triglycerides (TG) level, high density lipoprotein (HDL) cholesterol, low (LDL) very-low-density (VLDL) atherogenic (AI) measured. Results. Group 1 26 (HOMA-IR ˃ 2.7); 2 – 15 without ˂ 2.7). had severe course TB fever, fatigue weakness, profuse sweating, weight loss, cough shortness breath. Median TC indices differed at significant (p = 0.012): group 4.82 mmol/l, 4.25 mmol/l. TG was higher 1.32 mmol/l than 1.28 LDL values 3.2 vs 2.5 2. AI group1 0.005): 3.9 units against 2.8 patients. Conclusions. associated disease, clinical manifestations impaired external respiration. Pro-atherogenic disorders can be considered as degree endogenous intoxication.